The drug is injected into the amyide plates that accumulate in the brain several years before the symptoms appear.
A test treatment promised early results Reduce the risk of old age Related to him Alcellus In non -symptomatic patients, they predict the neurodegenerative disease. Researchers followed a small group of 22 patients Genetic changes It causes excessive production in the brain.
That is one of the characteristics of Alzheimer’s disease Amaloid protein It sticks and shapes the plates in the brain. According to the new inventions published The magazine ‘lanset neurology’When 22 patients were taken An anti -amaloid drug They have seen how they have been called Conduerumab for eight years The risk of forming symptoms went from 100% to 50%.
“All the participants in this study Alzheimer is destined to develop the diseaseSome of them have not yet done so, ”said Randal Batman, a professor of Neurology of the University of Washington (USA) and one of the research teachers.
“To give the best opportunity to be (for patients) to be inherently natural, we continued Treatment Con Another antifamily antibody They believe that they will never create symptoms, “Batman also said that the results suggest that early treatment may delay the appearance of Alzheimer’s symptoms.
A test with “wonderful” results
Las Benefits of cognitive They were found among the patients received Treatment for eight yearsOthers, though only two or three years, have not shown a significant improvement. It suggests that it should be useful Preventive therapy It may be necessary for many years to create symptoms of someone.
Charles Marshall described the results of the study in London (United Kingdom) Queen Mary Professor Charles Marshall of “very exciting” In a statement, but exemplifies the two limitations of the study.
“First, this is a secondary assessment Relatively small number of people They were held for a long time, so they were not safe if the results were the main result of the investigation, ”he said.
“The other limit is not even Kandanerumab Useful This suggests that, as well as other present amyroid reducing treatment that is currently available We can do more better What are these results, ”Marshall added.
Review the drug to prevent Alzheimers
He Contenerumab was suspended in 2022 Because he failed to slow down the signs of the most common forms Alzierrer disease In an article with over 1,900 participants. Need additional research to evaluate The possibility of anti -amiloid drugsThe best period of treatment and its effects on non -genetic forms of the disease, as well as potential side effects.
Anti -AMULOID drugs, for example, related Side effects Contraindications in brain scanners and locked inflammation. Although most of these side effects are resolved by them, some may change. In the article, Two participants had to stop taking medication Researchers said that due to side effects, but no death adverse effects.
