400,000 people in Spain suffer from schizophreniaIt refers to about 1% of the population. We still don’t understand What is the cause of this severe mental illnessBut we have identified some genetic factors that significantly increase the risk of being affected.
Now, a new study published in the educational environment of the big ka ti rav Hygiene Schizophrenia: He has discovered that our body is an unexpected part of the retina, and especially its thickness, which can provide important information on the genetic impact on its thickness. This may be the discovery Important applications for forecasting the conditionChanges in the retina are easily detected by seamless and low -test tests.
Window to the retina, the central nervous system
The retina, which is part of the eye Light sensitivity cells What we see in the form of electrical impulses is the outer part of the central nervous system, and has direct contact with our brain, so it is a possible feature to detect post -changes.
Keep in mind that many previous studies have documented that schizophrenia is associated with Configuration and functional changes in the central nervous systemIt also saw that it affects the retina of the people in a certain adrabi form. However, what is unknown until now is that the changes in the retina described in the retina of the disease are preceding the appearance of the disorder.
However, there is a fact that provides a revelation path: the thin of the retina is found in some earlier studies Relatives of the first degree of people in schizophrenia But the position did not develop themselves.
As a risk biomaritzer
The University of Zurich and the University of Surich Psychology Hospital (both in Switzerland) received information from 34,939 British and Irish persons compiled in the UK Biopank database. Genetic Analysis and Optical Coharans Tomography (A image technique used to evaluate the position of the retina).
Polygenic marks after being assigned to these people Genetic risk factors for schizophrenia It was collected in each case, crossing the data of the eye test, and taking into account the third factors that distort the results, and found that there was a communication between the two events.
Based on this, researchers conclude that changes such as genetic risk factors for schizophrenia are in the central nervous system They affect the thickness of the retina.
Possible initial diagnostic method
According to theory, these changes may be due to the expression of a particular genes associated with mental illness A neuro inflammation process In the waterfall that affects the retina structure, the result is changes.
Teachers believe that this invention provides important information on our understanding of schizophrenia because this may give us clues Neurological processes leading to it.
In the same way, they believe that the results support the results, even if they warn that this point should be confirmed by more large population studies The possibility of retinal measurementsAlso, especially the optical cooperation tomography, such as image tests, reliable tools, small prices and the early diagnosis of the disease are not very aggressive.
Notes
Rab, F., Smikelski, L., Georgis, F. And many others. Genetic damage to schizophrenia with neuro inflammatory paths associated with thinness of the retina. Natural mental health (2025). DOI: https://doi.org/10.1038/s44220-025-00414-6
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