Amytosis, known as SO-, is a rare disease in Spain, which is triggered during A The protein called amyide is placed in the organs Irregularly, these organs should not work as you do. From Through the kidneys or liver, to the heart, the spleen, the nervous system or the digestive tractThere are many parts of the body that can experience this important discipline.
The manifestation of this disease may be different than others, which can cause confusion among doctors based on the diagnosis, which can take up to four years. In the words of Dr. Raman Legambari Vilamatia, the co -director of the Navara Clinic’s Hematology and Hemo Therapy Service, “Essential Correctly identify the type of protein that is deposited As a material, the treatment varies depending on it. “
What type of amytosis is, any type of protein can be involved
Gathers amydeosis A plural of diseases They explain that “it has unusual folds of a pioneer protein, which ends in the form of fibrler structures that change its function in various organs and systems (heart, kidney, liver, intestine, nervous system).” University of Navara Clinic.
Overall, so far, they have been described 30 proteins involved in the appearance of different types of amytosis, In order to change the most effective treatment, it is important to know how to identify which type of protein is responsible for the ‘unusual’ deposit in each situation.
These are the symptoms of amytosis
Because this disease affects the large number of organs, Early diagnosis is very important to prevent these organs from getting worse Unchanged, the symptoms are not mentioned and differ from one person to another (even among the victim of the same family).
When victims are kidneys, the most common is the loss of protein, especially albumin, through urine (Proteinaria). When albumin levels descend into the blood, common edemans may appear. If the protein accumulation organ is the heart, the manifestations are a Cardiac dysfunction: Fatigue, arrhythmia, external edema and fatigue When making efforts.
If amoid deposits develop in the peripheral nervous system, the feeling of contraction in the anxiety and hands. When it affects the digestive tract, bad foods are triggered by the absorption and some intestinal movement, with Diarrhea (sometimes bleeding) or constipation Extreme.
Why does amaloidosis confuse doctors?
When experts talk about this difficult diagnosis Hereditary disease. So it may take years for the diagnosis.
In most cases, a Infected tissue biopsy In this, the presence of amyide deposits is proven by staining the redness of the Congo. Although it is necessary to sometimes make a kidney or cardiovascular biopsy, The most common is the biopsy of the abdominal fat, Bone marrow or meadulla.
As for risk factors, beyond the hereditary components, the advanced age is solitary (Most diagnoses are about 65 Age). In addition, experts warn that there is an infectious disease or suffering Chronic inflammation Increases the risk of a type of amyradosis. Dialysis is another entry door of the pathology, because with this technique, unusual proteins can accumulate in the blood and deposit into the tissues.
Notes
On the FL side, M.J. ‘Amytosis’. University of pathological anatomy of Santiago de Campostela. Vol. 36. No. 4. Published in Elsevier Medicin’s magazine. Advice online https: // www April 7, 2025.
