He Medical hospital Has exceeded 500 patients with blood cancer and they have been treated since 2017 Advanced Immunization Car-D With good results, then Cancer disappears in half of them is now seenCalled complete relief.
Clinic Hospital in Barcelona is aware of this week CAR-T (for its summary in the English Symetric antigen receiver T-Selv or T-cells in the Ceramic antigen recipient of the cells)It is used in acute lymphoplastic leukemia, many myeloma and lymphoma.
CAR-T treatment is the extract of their D lymphocytes (immune system cells) from the patient and genetically modified to attack cancer cells Introduce them to the body.
Last chance
They treat them They only apply to patients who have already passed all regular treatment taxes (Such as chemotherapy or marrow transplantation) and not working.
The clinic is Two industrial treatments . Acute lymphoplastics And Ari -0002h for adults Many mulomaAnd the medical test of ARI -0003 is underway Lymph.
In Spain they have 300 to 400 patients per year with car-D, only 6% of countries accessible treatment
In 2017, the first patient was treated in the clinic, with a govt infection in between, in six years, Car-T first 502 patients have been used, With a climbing rhythm: from 11 to 103 in 2017 to 2024. Of the more than 500 patients, 70 % are not a clinic from other hospitals in Spain.
Co-t program coordinator Medical-Idibabis. Half reached complete relief of “transparent” disease.
Relief, not total treatment
This means that after treatment, cancer is not detected in the body, but It may not be equal to a healing because it may be reincarnated A few years later.
Positive response to CAR-T treatment and the risk of rebirth Vary depending on the disease, He has pointed out the urban.
The first CAR-T (ARI -0001) is treated, so there are more cases in which it is. This is a severe lymphoplastic leukemia, of which 90% of patients achieve total relief The disease is, but only 30% after 4 years is in this position. In many myeloma, the percentage of relief is 60%and less than 50%.
However, they are already suitable for those who have passed all the usual treatment without success and they are There are no treatment options.
Ary’s “miracle”
One of the successful events, Salvia Royra, a patient who was treated with the Ari -0002H car, thanked this Wednesday “Social and Health Miracle” The teenager carried out Haryana ‘Ari’ BenateHe said he could give a year of life.
Ari arrived at Hospital Clinic Hospital in 2015 as he fell from a severe lymphoplastic leukemia and launched a host campaign Can bring car-D treatment to BarcelonaLater in Spain, it began to match in the United States.
She could not benefit He died at the end of 2016 with 18 yearsBut its effort has turned into an ARI project and allowed more than 500 people to be treated.
Car-T’s growth in clinic-Etipaps has the initial stimulation of the ARI program With the support of the “La Kaisa” Foundation.
The challenge of access
Lo-D treatments material A revolution in customized medicine against cancer, But the beneficial patients are still less, and Manal Juan, the head of the Clinic Immunology Service, agreed.
Spain They are 300 to 400 patients per yearIn a treatment that contains only 6% accessible in industrialized countries.
As for the clinic’s carriage, the network has been extended to reach more people from all over Spain: present Three production centers Treatment – Clinic, Sand Joan de Dew (Esplux de Laloprigat) and Clinica Universidat de Nawara- and 13 hospitals administrators.
First car-D treatment for MMRR
It has been revealed this week First Cart-T cell therapy for regeneration and useless muloma patients (MMR) is already available in Spain since April 1, after it has been detected that this curable blood cancer is significantly improved.
Johnson & Johnson has announced that it is a new genetically converted tool called Garvigty It reaches health centers for adult patients with multiple myeloma In the absence and ineffectiveness of at least one previous treatment, they have come up with the last treatment of the progression of the disease, and are ineffective for sustainable treatment with lenolidomide.
This first recognized car-de cell treatment Allowed to be 70% free of treated patients This type of blood cancer is affecting a type of white blood cells known as plasma cells found in bone marrow. Overall, 13 centers across Spain have participated in the development of this car-D treatment, first recognized by the European Commission for these patients.
According to the Spanish Society of Medical oncology (SEOM), it is estimated in our country In 2025, they will be diagnosed with 3,700 new cases of irreversible cancer. So this “important biological discovery” means “a new science milestone and a paradigm change”.