Over time and from 50 Women begin to experience symptoms such as shortness of breath, night sweating, muscle mass loss, OsteoporosisIt can lead to osteoporosis … may have different effects at this point, it can even Increase the risk of certain diseasesDue to the decrease in the amount of estrogen. Liver pathology is an example of this, in particular, we are talking about chirosis, according to Spanish experts after fibrosis.
The Germans led a study published in the Triyas IGDP Research Institute (IGDP) researchers Laboratory animals This is the first time, evaluating the difference between sex against liver disease during an advanced stage in the rat model. Experts have analyzed two types of liver diseases They are often offered in menopause women. Find out what its symptoms are and what influence this pathological climate.
How does menstruation affect the liver?
A team of researchers shows that liver diseases are different in the development and evolution between men and women. Estrogens play a protective roleSo women have some protection for the progress of the disease. It directly affects the menstrual stop At this point the amount of estrogen decreases, among other thingsTherefore, women with menstruation have a high irrigation of liver disease.
In fact, the Menopause According to a study carried out in it The energy metabolism and nutritional group of energy From the UIP (University of the Balleric Islands) carried out in rats and vitro, estrogens provide a wide range of protective effects on the liver. It is significantly related to the progress of mitochondrial activity and regulating fats in the liver cells. That is why, ”Increases the risk of liver disease after menstruation“. According to the above study, the differences between sexes are found in humans and animal samples used in premature studies.
However, traditionally most research in mice and mice has not taken these differences into account, and is only done in men. Studies of liver fibrosis used by both sexes They focus on the role of sex hormones In the early stages of his progress, he set aside the liver Sirasosis. In another study, the effect of the sex was determined in a chirosis model with askites in the mice described only for men.
In this way, the liver is repeatedly repeated, by managing carbon tetrachloride, and changing their dosage until the appearance of ascites. The answer of men and women is different. “Men developed ascites at the time of the sample supplied, while women made only twice as much as they could point out, and experts only made it easier for the toxicity and regenerative response of carbon tetrachloride.
What is fibrosis and liver chirosis?
Is there Various variations between fibrosis and chirosis. To determine what fibrosis is, according to IGDP experts, we need to know that when an organ is injured, our body begins a healing process. If the sore is repeated or chronic, it can lead to an excessive accumulation of fiber tissue and can cause changes in the structure and function of the affected organ. This phenomenon is called fibrosis.
Fibrosis can affect the kidneys, lungs, heart and liver. The latter, advanced fibrosis It can develop toward the liver chirosphiesThe latest and most irreversible phase of liver disease, where secondary complications, such as ascites, are provided, accumulation of fluid in the abdomen.
When they point out as they are shared The National Institute of Diabetes and Digestive and Kidney Diseases Siriosis is a condition that can heal and permanently damage the liver. The scar tissue replaces healthy liver tissue and prevents the liver from working normally. The scar tissue is somewhat preventing blood flow through the liver. When chirosis worsens, the liver begins to fail.
Many people do not know that they have chirosis because they have no symptoms or symptoms until the liver is seriously damaged. For this reason, deciding what they are, and they can soon identify them at the right time to stop the disease. The first effects exposed According to experts, they are:
- The feeling of fatigue or weakness
- Itching in the skin
- Anatomy
- Accidental weight loss
- Nausea and vomiting
- In the area where the liver is located, mild pain or ascetic om charcoal, ie on the upper right of the abdomen (belly)
- Loss and muscle weakness, Something often happens at the menstrual stop.
- Muscle spasms
- Sexual problems
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Notes
Ibora I, Bartoli R, Barkalle A, and many others. The impact of sexual differences in the end -stage liver disease of the rat model of the clinical symptoms and the evolution of evolution. Laboratory animals. 2025. Doy:10.1177/0023672241309760